Endocrine Abstracts

Introduction: During adrenal insufficiency (AI), glucocorticoid treatment is supposed to be neutral on the metabolic parameters of patients. However, recent data from the literature report that this corticosteroid replacement therapy increases the metabolic risk. The aim of our work was to determine the metabolic and cardiovascular impact of hydrocortisone (HC) replacement therapy during peripheral AI.Patients and methods: This was a descriptive and anal...

Introduction: Hydrocortisone (HC) is the most widely used replacement molecule in the treatment of adrenal insufficiency (AI). This substitution treatment is far from ideal especially as it is impossible to reproduce the nycthemeral cycle of cortisol with its current galenic form which has a short half-life. The aim of our work was to determine the impact of HC treatment of peripheral AI on the long-term quality of life and sleep.Patients and methods: Th...

Introduction: The treatment of adrenal insufficiency (AI) is based on long-term glucocorticoid substitution. Hydrocortisone (HC) is the most commonly used substitution molecule. The aim of our work was to determine the long-term bone impact of patients with peripheral AI.Patients and methods: This is a descriptive and analytical study involving 77 patients with peripheral IS (66 women and 11 men), all treated with HC. For each patient, we determined the ...

Introduction: Diabetes mellitus (DM) and depression are two frequent health conditions. Their coexistence may represent a medical challenge for clinicians. In addition, early detection of depression can help in better management of diabetes and preventing its complications.Aim of the study: To assess depression and glycemic control among a group of patients having diabetes.Methods: A cross sectional study was conducted among diabet...

Introduction: Medication Adherence (MA) is the extent to which patients follow medical instructions. Poor MA is frequently encountered in the majority of chronic diseases, including diabetes. The aim of our study was to evaluate MA in patients with poorly controlled type 2 diabetes mellitus (T2DM).Patients and methods: We conducted a cross-sectional study over a period of 2 months, including patients with poorly controlled T2DM, followed at the endocrino...

Introduction: Nutrition is a cornerstone of the adequate management of Type 2 diabetes mellitus (T2DM). The aims of our work are to evaluate the degree of observance of dietary rules in T2DM patients, and the factors that influence this observance.Methods: Cross-sectional study including 84 type 2 diabetic patients followed up in the outpatient endocrinology department of Taher Sfar university hospital from September to November 2021. The data was collec...

Introduction: Thyroid diseases have been known to cause haemostatic changes, either tendency to bleeding or thrombosis. We report a case of a patient with primary hypothyroidism presenting with spontaneous bleeding and jugular thrombosis.Case report: An 85-year old patient with no medical history was admitted to the endocrinology department with primary auto-immune hypothyroidism. Hypothyroidism was suspected because of severe loss of weight and appetite...

Introduction: The obstructive sleep apnea syndrome (OSAS) has a well-documented association with increase cardiovascular morbidity and mortality. The patients with OSAS have a high prevalence of hypertension (HTA).Case report: A 52-year-old female with a history of poorly controlled resistant HTA was admitted to our hospital with severe HTA. She had a history of fatigue and intermittent episodes of palpitations. Laboratory evaluation was significant for ...

Objective: To determine the relationship between metabolic syndrome (MS) and cognitive decline in type 2 diabetes patients over 65 years age.Methods: The age of the participants were between 60 and 87 years old. According to NCEP ATP III criteria 30 had MS and 28 had not. Cognitive performance was determined with the use of standardised mini mental test and the mini mental scores (MMS) of the two groups were compared. Apart from the MS we investigated th...

Introduction: Empty sella in male patients is a very rare situation. It could be diagnosis in acquired male hypogonadotropic hypogonadism or hypopituitarism.Case report: A 55-year-old type 2 diabetes male was referred to our hospital with erectile dysfunction (ED). He has three children. His secondary sex characteristics, sexual function, and ejaculation were previously normal but for the last 3 years he had ED. His genital stage was Tanner V, and pubic ...